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John Hiscott Selected Research

interferon regulatory factor-4

1/2005Repression of DNA repair mechanisms in IRF-4-expressing and HTLV-I-infected T lymphocytes.
1/2002IRF-4 activities in HTLV-I-induced T cell leukemogenesis.

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John Hiscott Research Topics

Disease

41Infections
01/2022 - 04/2002
36Virus Diseases (Viral Diseases)
10/2020 - 03/2002
27Neoplasms (Cancer)
01/2021 - 06/2002
13Vesicular Stomatitis
01/2019 - 10/2004
7Bites and Stings (Sting)
11/2021 - 06/2010
6RNA Virus Infections
08/2015 - 06/2006
5COVID-19
01/2022 - 10/2020
5Dengue (Dengue Fever)
01/2020 - 04/2014
5Human Influenza (Influenza)
01/2017 - 08/2005
4Lymphoma (Lymphomas)
10/2014 - 08/2005
3Prostatic Neoplasms (Prostate Cancer)
01/2019 - 11/2013
3T-Cell Leukemia (Leukemia, T Cell)
12/2014 - 09/2002
3Hodgkin Disease (Hodgkin's Disease)
10/2014 - 02/2003
3B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2013 - 09/2008
3Melanoma (Melanoma, Malignant)
07/2006 - 09/2002
3Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2005 - 01/2002
2Pneumonia (Pneumonitis)
01/2022 - 01/2013
2Cytokine Release Syndrome
01/2022 - 09/2015
2Shock
11/2021 - 01/2019
2Adenocarcinoma
12/2020 - 11/2013
2HIV Infections (HIV Infection)
10/2016 - 08/2012
2Carcinoma (Carcinomatosis)
10/2015 - 08/2005
2Tropical Spastic Paraparesis (Tropical Spastic Paraplegia)
11/2007 - 01/2002
1Malaria
11/2021
1Inflammation (Inflammations)
11/2020
1Herpes Simplex
10/2020
1Cytomegalovirus Infections (Inclusion Disease)
01/2020

Drug/Important Bio-Agent (IBA)

39Antiviral Agents (Antivirals)IBA
11/2021 - 06/2002
15InterferonsIBA
01/2022 - 01/2002
15Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2002
14Interferon Type IIBA
08/2021 - 06/2002
10Transcription Factors (Transcription Factor)IBA
01/2017 - 09/2002
10Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA
06/2009 - 06/2002
9CytokinesIBA
01/2022 - 06/2002
7DNA (Deoxyribonucleic Acid)IBA
11/2019 - 03/2002
7RNA Helicases (RNA Helicase)IBA
02/2011 - 02/2006
6ChromatinIBA
01/2021 - 08/2005
6Phosphotransferases (Kinase)IBA
01/2020 - 05/2003
6RNA (Ribonucleic Acid)IBA
09/2019 - 06/2009
6NF-kappa B (NF-kB)IBA
01/2014 - 04/2002
5Histone Deacetylase InhibitorsIBA
11/2019 - 09/2008
5Tretinoin (Retinoic Acid)FDA LinkGeneric
09/2019 - 07/2006
5Small Interfering RNA (siRNA)IBA
01/2019 - 11/2009
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2015 - 09/2002
5Viral RNAIBA
10/2015 - 08/2009
5LigandsIBA
10/2015 - 06/2002
5Interferon Regulatory FactorsIBA
10/2014 - 04/2002
5I-kappa B KinaseIBA
06/2009 - 10/2004
4ChemokinesIBA
01/2022 - 06/2002
4VaccinesIBA
01/2022 - 10/2012
4Toll-Like Receptors (Toll-Like Receptor)IBA
11/2021 - 11/2006
4AntioxidantsIBA
11/2020 - 12/2014
4UbiquitinIBA
10/2016 - 10/2006
4Biological ProductsIBA
12/2011 - 06/2003
3Pharmaceutical PreparationsIBA
11/2021 - 06/2003
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 12/2014
3Peptide Hydrolases (Proteases)FDA Link
11/2020 - 12/2007
3cyclic guanosine monophosphate-adenosine monophosphateIBA
11/2019 - 01/2017
3LipopolysaccharidesIBA
10/2011 - 09/2002
3Interferon-betaIBA
07/2007 - 06/2002
3Double-Stranded RNA (RNA, Double Stranded)IBA
07/2006 - 03/2003
3Messenger RNA (mRNA)IBA
02/2006 - 06/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2022 - 12/2011
2Neoplasm Antigens (Tumor Antigens)IBA
12/2020 - 12/2011
2Oncogene Proteins (Oncogene Protein)IBA
01/2020 - 09/2002
2Nucleic AcidsIBA
01/2020 - 07/2012
2triphosphoric acid (triphosphate)IBA
09/2019 - 01/2013
2Histone Deacetylases (Histone Deacetylase)IBA
01/2019 - 11/2007
2Trans-Activators (Trans-Acting Factor)IBA
10/2016 - 08/2005
2Ligases (Synthetase)IBA
10/2016 - 10/2006
2Interleukin-6 (Interleukin 6)IBA
10/2015 - 09/2002
2Pattern Recognition ReceptorsIBA
01/2014 - 08/2011
2Pathogen-Associated Molecular Pattern MoleculesIBA
01/2014 - 08/2011
2obatoclaxIBA
07/2013 - 12/2010
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
06/2011 - 02/2006
2Antineoplastic Agents (Antineoplastics)IBA
06/2010 - 09/2008
2Interferon-alpha (Interferon Alfa)IBA
04/2006 - 06/2002
2InterleukinsIBA
08/2005 - 06/2002
2interferon regulatory factor-4IBA
01/2005 - 01/2002
2Phospho-Specific AntibodiesIBA
12/2003 - 03/2003
2Chemokine CCL5IBA
09/2002 - 06/2002
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2022
1Atovaquone (Mepron)FDA Link
11/2021
1proguanil drug combination atovaquone (malarone)FDA Link
11/2021
1Sirtuin 2IBA
01/2021
1Anti-Bacterial Agents (Antibiotics)IBA
01/2021
1Glutathione (Reduced Glutathione)IBA
01/2021
1Liposomes (Liposome)IBA
01/2021
1MicroRNAs (MicroRNA)IBA
01/2021
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2020
1CarcinogensIBA
01/2020
1resminostatIBA
11/2019
1Cyclic NucleotidesIBA
11/2019
1CaspasesIBA
09/2019

Therapy/Procedure

16Therapeutics
12/2020 - 11/2006
4Immunotherapy
01/2021 - 01/2017
4Oncolytic Virotherapy
12/2020 - 06/2010
2Highly Active Antiretroviral Therapy (HAART)
11/2021 - 01/2019
2Investigational Therapies (Experimental Therapy)
01/2021 - 12/2011
1Chemoprevention
11/2021